The Effects of a Commercially Available Weight Loss Program Among Obese Patients with Type 2 Diabetes:

A Randomized Study

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Gary D. Foster, PhD, Kelley E. Borradaile, PhD, Stephanie S. Vander Veur, MPH, Kerri Leh Shantz, MPH, Rebecca J. Dilks, RD, Edie M. Goldbacher, PhD, Tracy L. Oliver, PhD, RD, Caitlin A. LaGrotte, MEd, Carol Homko, PhD, RN, Wayne Satz, MD

Table of Contents

Postgraduate Medicine:

Volume 121 No. 5

Category:

Clinical Focus

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DOI: 10.3810/pgm.2009.09.2046
Abstract: The purpose of this study was to assess the effects of a commercially available weight loss program on weight and glycemic control among obese patients with type 2 diabetes. Participants included 69 patients (49 females, 20 males) with type 2 diabetes who had a mean ± SD age of 52.2 ± 9.5 years, a body mass index of 39.0 ± 6.2 kg/m2, and hemoglobin A1c (HbA1c) of 7.5 ± 1.6%. Over half (52.2%) of the participants were African American. Participants were randomly assigned to: 1) a portion-controlled diet (NutriSystem® D™) (PCD) or 2) a diabetes support and education (DSE) program. After the initial 3 months, the PCD group continued on the PCD for the remaining 3 months, and the DSE group crossed over to PCD for the remaining 3 months. The primary comparison for this study was at 3 months. At 3 months, the PCD group lost significantly more weight (7.1 ± 4%) than the DSE group (0.4 ± 2.3%) (P < 0.0001). From 3 to 6 months the change in weight for both groups was statistically significant. After 3 months, the PCD group had greater reductions in HbA1c than the DSE group (−0.88 ± 1.1 vs 0.03 ± 1.09; P < 0.001). From 3 to 6 months the PCD group had no further change in HbA1c, while the DSE group showed a significant reduction. These data suggest that obese patients with type 2 diabetes will experience significant improvements in weight, glycemic control, and cardiovascular disease risk factors after the use of a commercially available weight management program.

Keywords: obesity , type 2 diabetes , commercial weight loss program , portion control